Bone Hormone Affects Our Appetite And Metabolism Of Fat And Sugar: Study

Bone Hormone Affects Our Appetite And Metabolism Of Fat And Sugar: Study

In a new study, researchers have figured out more about how a hormone produced by our bones that affects how we metabolize sugar and fat and more specifically the bone cells that produce them, play a far more active role in our bodies than we generally consider.

Researchers from the Montreal Clinical Research Institute (IRCM) in Canada studied this hormone known as Osteocalcin produced by our bones that affects how we metabolize sugar and fat.

According to study, the hormones produced by bone cells, helps sugar metabolize sugar more easily. One of the osteocalcin’s functions is to increase insulin production, which in turn reduces blood glucose levels.

The discovery may someday open the door to new ways of preventing type 2 diabetes and obesity. The removal of this famous “scissors” in bone cells has also had an unexpected effect: a decrease in appetite in mice.

“One of the osteocalcin’s functions is to increase insulin production, which in turn reduces blood glucose levels,” said one of the researchers Mathieu Ferron from Montreal Clinical Research Institute (IRCM) in Canada.

“Osteocalcin helps, among other things, to produce insulin, which lowers the level of glucose in our blood. It could also protect us from obesity by increasing our energy expenditure,” said Ferron.

“We demonstrated that when there was no furin in bone cells, inactive osteocalcin built up and was still released, but this led to an increase in blood glucose levels and a reduction in energy expenditure and insulin production,” Ferron said.

Studies even indicate that changes in blood levels of osteocalcin may influence the development of diabetes in some people. The researchers also revealed the puzzle that explains how osteocalcin works.

Osteocalcin is produced by single nucleus cells called osteoblasts, which are responsible for bone building. The study was published in the scientific journal The Journal of Clinical Investigation.

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